In vitro Anti-Urolithiatic Activity & Determination of Flavonoid Contents of Different Extracts of Citrus Sinensis Leaves
Author : Dr. Nilesh V Desai
Abstract :
The most typical urinary tract condition is urolithiasis. Despite enormous medical advancements, there is still no truly effective therapy to treat renal calculi, despite the large incidence of urolithiasis in the world. Pharmacologists should pay particular attention to Citrus Sinensis' widespread use in treating kidney stones & other problems of the urinary tract. However, it is challenging to find studies that explain Citrus Sinensis' antiurolithiatic effect. It has a traditional claim for diuretic & kidney disorders. Its usage in urolithiasis has not been well supported scientifically. Therefore, the current study was conducted to investigate Citrus Sinensis' antiurolithiatic characteristics. The Methanolic Extract of Citrus Sinensis (MECS) leaves were investigated for their in vitro antiurolithiatic activities in the current study employing a crystal aggregation assay. In the current investigation, MECS significantly decreased crystal aggregation. In the current work, a total flavonoid content assay was used to confirm the presence of flavonoids in different extracts of Citrus Sinensis.
Keywords :
Urolithiasis, citrus sinensis, flavonoid, MECS
