Ayurvedic Approaches of Drug-Induced Immunosuppression through Agad Tantra Principles
Author : Dr. Mahesh V Patil
Abstract :
Agad Tantra is one of the branches of Ayurveda, focusing on toxicology, specially the diagnosis and treatment of diseases caused by animate (Jangam and Sthavar) & artificial sources. Drug-induced immunosuppression has emerged as a major clinical challenge due to the extensive use of corticosteroids, immunomodulators, chemotherapeutic agents, and biologics in modern medical practice. Prolonged administration of these drugs leads to suppression of immune responses, resulting in increased susceptibility to infections, delayed wound healing, metabolic disturbances, and systemic debility. In Ayurveda, such a condition can be correlated with Ojokshaya, BalaKshaya, and Vyadhikshamatva Hani, where depletion of Ojas—the essence of all Dhatus—leads to compromised immunity and vitality. Ayurveda defines immunity as an integrated function of Agni, Ojas, Bala, and equilibrium of Doshas and Dhatus. This review critically analyzes drug-induced immunosuppression through modern biomedical concepts and correlates them with Ayurvedic principles such as Tikshna Virya, Visha-sadrusha Guna, Agni Dushti, and Dhatu Kshaya. Ayurvedic management strategies including Rasayana Chikitsa, Panchakarma, dietary regulation, herbal immunomodulators, and lifestyle interventions are discussed in detail. The article highlights Ayurveda’s potential as a supportive and restorative system in managing drug-induced immunosuppression while improving overall health and resilience.
Keywords :
Drug-induced Immunosuppression, Ojas, Bala, Rasayana, Panchakarma, Vyadhikshamatva, Ayurveda.
