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Rasayana Chikitsa: Combating Oxidative Stress through Ayurveda

Author : Dr. Prakash Jondhale, Dr. Avdhesh Kumar Bhatt and Dr. Anita Mali

Abstract :

Oxidative stress, resulting from an imbalance between reactive oxygen species (ROS) generation and antioxidant defenses, is a key driver of aging and chronic degenerative diseases such as diabetes, cardiovascular disorders, neurodegeneration, and cancer. Modern antioxidant therapies, while effective in direct radical scavenging, often show inconsistent long-term outcomes and potential interference with physiological redox signaling. Ayurveda presents Rasayana Chikitsa as a dedicated branch for rejuvenation, promoting longevity, immunity, intellect, strength, and resistance to disease.
This conceptual study explores theoretical correlations between classical Ayurvedic principles and modern antioxidant mechanisms. Core concepts including Agni (metabolic fire), Ama (toxic metabolites), Dhatu poshana (tissue nourishment), Ojas (vital essence), and Jara (senescence) are interpreted in the context of redox homeostasis, cellular integrity, and systemic resilience. Through critical literary analysis, Rasayana Chikitsa emerges as a holistic, multilevel antioxidant strategy that prevents excessive ROS production at metabolic roots while enhancing endogenous defenses. Unlike reductionist approaches, it integrates pharmacological, dietary, behavioral, and lifestyle interventions for sustainable health promotion. The study provides a robust theoretical framework bridging ancient wisdom with contemporary science, advocating further empirical validation through experimental and clinical research.

Keywords :

Rasayana Chikitsa, Oxidative Stress, Antioxidant Therapy, Agni, Ama, Ojas, Jara, Ayurveda, Rejuvenation.