Determination of Viscosity of 4,5-Dihydro Substituted Oxazoles in DMF -Water Mixture
Author : Nilesh S Padole, Muralidhar P Wadekar, Gopalkrushna H Murhekar and Shubhangi Y Deshmukh
Abstract :
The present study focuses on the determination of viscosity of 4,5-Dihydro substituted oxazoles in DMF–water mixtures at various compositions and temperatures to understand solute–solvent interactions. The viscosity measurements were carried out using an Ostwald viscometer under controlled temperature conditions. The effect of solvent composition, concentration, and temperature on the viscosity of the substituted oxazoles was systematically studied. The experimental data were analyzed using Jones–Dole equations to obtain the viscosity A and B coefficients, which provide insight into the ion–ion and ion–solvent interactions, respectively. The results reveal that viscosity decreases with increasing DMF content due to a reduction in hydrogen bonding and cohesive forces in the medium. The positive values of the B-coefficient suggest strong solvation of the substituted oxazoles in the mixed solvent system. These findings contribute to a better understanding of the molecular interactions and structural behavior of oxazole derivatives in mixed solvent environments, which is significant for their physicochemical and biological studies.
Keywords :
Viscosity, 4,5-Dihydro Substituted oxazoles, DMF–water mixture, Jones–Dole equation, Solute–solvent interaction.
