Treatment of Erythema Multiforme Induced by Antipyretics-Case Report
Author : Ambika Murari, Rajendragouda Patil, Arjit Vihan, Angshuman Sarma and Paridhi Agarwal
Abstract :
Erythema multiforme (EM) is an acute condition driven by the immune system, featuring the rapid emergence of distinct target-like lesions on the skin and mucous membranes. It usually presents symmetrically, most commonly affecting the extremities, and its severity can range from mild (EM minor) to severe (EM major). The condition is usually triggered by infections, especially the herpes simplex virus (HSV), but can also be caused by certain medications, vaccines, and other factors. Its pathogenesis involves a complex interaction between the immune system and epithelial cells, resulting in cell-mediated cytotoxic responses. Clinically, patients may exhibit initial symptoms such as fever, malaise, and upper respiratory issues, followed by the development of lesions that progress over several days. Diagnosis primarily relies on clinical evaluation, complemented by histopathological evidence showing interface dermatitis with necrotic keratinocytes. Management strategies aim to identify and remove the triggering factor, offering symptomatic relief through antihistamines, analgesics, and topical corticosteroids for mild cases, while severe cases may require systemic corticosteroids or immunosuppressive agents. Here, we are presenting a case of erythema multiforme in 27 years 27-year-old male.
Keywords :
Erythema multiforme, antipyretics, oral cavity
