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The Effect of Terminalia chebula on Resistance to Hydrogen Peroxide Induced Oxidative Stress in Drosophila melanogaster

Author : Chaithra Bhoomi Rakkhitha DK and V Shakuntala

Abstract :

Oxidative stress induces to production of free radicals in all cells due to cellular metabolism reflected also by environmental factors. Accumulated free radicals has many negative effects on the cell including cellular aging, hence the present project is their nutritional impact on the stress resistance and production of free radicals using some phytochemicals. Terminalia chebula (one of the Triphala) was used in ancient medicine to cure many ailments, most of the disease are positively correlated with stress. Drosophila melanogaster flies exposed H2O2 and those treated with T.chebula exhibited more resistance to oxidative stress. The age of the flies enhanced to 10 hours, in a dose dependent manner.

Keywords :

Terminalia chebula, Drosophila melanogaster, hydrogen peroxide, oxidative stress and Antioxidants