Effect of the Terminalia chebula, one of the Constituent of Triphala on Climbing Ability of Drosophila melanogaster
Author : Priyanka S, Saraswathi and Shakunthala V
Abstract :
This study investigates the effect of Terminalia chebula on the climbing behavior of Drosophila melanogaster. The climbing assay, a measure of motor function, was conducted on both 5-day-old and 20-day-old male and female flies raised on control and treated media. The treated groups received either 250 mg or 300 mg of Terminalia chebula. The results showed a significant improvement in climbing ability in flies treated with Terminalia chebula compared to the control group. Notably, the 300 mg treatment group exhibited the highest climbing performance across all age and sex groups, with males outperforming females in both control and treated conditions. Age-related differences were evident, with younger flies (5 days old) displaying superior climbing ability compared to older flies (20 days old). These findings suggest that Terminalia chebula enhances motor function and may mitigate age-related declines in Drosophila melanogaster. The study highlights the potential of Terminalia chebula as an antioxidant, neuroprotective, anti-inflammatory, and metabolic-enhancing effects, warranting further research to elucidate the underlying mechanisms and its applicability to other species.
Keywords :
Drosophila melanogaster, Terminalia chebula, climbing ability
