Creatine Monohydrate Decrease Longevity in Drosophila Melanogaster
Author : Sithembiso Sebastian Mamba and Mysore Siddaiah Krishna
Abstract :
Creatine monohydrate supplement usage has surged nowadays. It is however unknown whether it has benefit or detrimental effect on organisms fitness other than the well-researched ergogenic effect. The current study has been undertaken to find the effect of creatine monohydrate on longevity in Drosophila melanogaster. In the current study, Drosophila melanogaster longevity was investigated using flies fed control media and creatine monohydrate supplement treated media at different concentrations (2.5%, 5% and 10%). It was observed that control flies lived noticeably longer than flies maintained on creatine monohydrate supplemented media in both sexes. However, females showed longer survival time compared to male flies. The study further revealed that longevity decrease with increase in creatine monohydrate supplementation. The results demonstrated that creatine monohydrate reduce longevity in D. melanogaster.
Keywords :
Longevity, Creatine monohydrate, and Drosophila melanogaster
